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Drug Name | ZSTK474 |
Trade Name | |
Synonyms | ZSTK-474 |
Drug Descriptions |
ZSTK474 is a pan-PI3K inhibitor, which blocks PI3K/AKT signaling to prevent cell growth (PMID: 16622124, PMID: 30205797). |
DrugClasses | PI3K Inhibitor (Pan) 42 |
CAS Registry Number | 475110-96-4 |
NCIT ID | C95723 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Imatinib + ZSTK474 | Imatinib ZSTK474 | 0 | 0 |
Nilotinib + ZSTK474 | Nilotinib ZSTK474 | 0 | 0 |
Olverembatinib + ZSTK474 | Olverembatinib ZSTK474 | 0 | 0 |
PD-0325901 + ZSTK474 | PD-0325901 ZSTK474 | 0 | 0 |
R11.1.6 + ZSTK474 | R11.1.6 ZSTK474 | 0 | 0 |
Ruxolitinib + ZSTK474 | Ruxolitinib ZSTK474 | 2 | 0 |
Selumetinib + ZSTK474 | Selumetinib ZSTK474 | 1 | 0 |
Vemurafenib + ZSTK474 | Vemurafenib ZSTK474 | 1 | 0 |
ZSTK474 | ZSTK474 | 0 | 0 |