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Drug Name | Tirabrutinib |
Trade Name | |
Synonyms | ONO-GS-4059|ONO-WG-307|ONO-4059|GS 4059|GS4059 |
Drug Descriptions |
Tirabrutinib (ONO-4059) is a selective inhibitor of BTK, which potentially induces antibody-dependent cell-mediated cytotoxicity against tumor cells and inhibits tumor growth (PMID: 27684575, PMID: 27776353, PMID: 32583848). |
DrugClasses | BTK inhibitor 38 |
CAS Registry Number | 1351636-18-4 |
NCIT ID | C102876 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Entospletinib + Obinutuzumab + Tirabrutinib | Entospletinib Obinutuzumab Tirabrutinib | 0 | 1 |
Entospletinib + Tirabrutinib | Entospletinib Tirabrutinib | 0 | 1 |
Idelalisib + Obinutuzumab + Tirabrutinib | Idelalisib Obinutuzumab Tirabrutinib | 0 | 1 |
Idelalisib + Tirabrutinib | Idelalisib Tirabrutinib | 0 | 1 |
Tirabrutinib | Tirabrutinib | 0 | 2 |