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Drug Name | Tirabrutinib |
Trade Name | |
Synonyms | ONO-GS-4059|ONO-WG-307|ONO-4059 |
Drug Descriptions |
Tirabrutinib (ONO-4059) inhibits Bruton's Tyrosine Kinase (BTK), which leads to decreased B-cell proliferation and differentiation, and may have antitumor activity in B-cell malignancies (PMID: 23958373, PMID: 27776353, PMID: 32156743). |
DrugClasses | BTK inhibitor 37 |
CAS Registry Number | 1351636-18-4 |
NCIT ID | C102876 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Entospletinib + Obinutuzumab + Tirabrutinib | Entospletinib Obinutuzumab Tirabrutinib | 0 | 1 |
Entospletinib + Tirabrutinib | Entospletinib Tirabrutinib | 0 | 1 |
Idelalisib + Obinutuzumab + Tirabrutinib | Idelalisib Obinutuzumab Tirabrutinib | 0 | 1 |
Idelalisib + Tirabrutinib | Idelalisib Tirabrutinib | 0 | 1 |
Tirabrutinib | Tirabrutinib | 0 | 2 |