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Drug Name | Idelalisib |
Trade Name | Zydelig |
Synonyms | CAL-101|GS-1101 |
Drug Descriptions |
Zydelig (idelalisib) inhibits PI3K-delta, preventing the activation of the PI3K signaling pathway and inhibiting tumor cell proliferation, motility, and survival (PMID: 24450857). Zydelig (idelalisib) is FDA approved for follicular B-cell non-Hodgkin lymphoma, relapsed small lymphocytic lymphoma, and in combination with Rituxan (rituximab) for relapsed chronic lymphocytic leukemia (FDA.gov). |
DrugClasses | PIK3CD inhibitor 27 |
CAS Registry Number | 870281-82-6 |
NCIT ID | C78825 |