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Drug Name AZD6482
Trade Name
Synonyms KIN-193|AZD-6482
Drug Descriptions

AZD6482 inhibits PIK3CB and PIK3CD, preventing the activation of the PI3K signaling pathway and inhibiting tumor cell proliferation, motility, and survival (PMID: 24992874, PMID: 23674493, PMID: 31292159, PMID: 30542720).

DrugClasses PIK3CB inhibitor 8 PIK3CD inhibitor 27
CAS Registry Number 1173900-33-8
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
A66 + AZD6482 A66 AZD6482 1 0
Alpelisib + AZD6482 AZD6482 Alpelisib 2 0
Alpelisib + AZD6482 + Binimetinib AZD6482 Alpelisib Binimetinib 1 0
Alpelisib + AZD6482 + Binimetinib + Encorafenib AZD6482 Alpelisib Binimetinib Encorafenib 1 0
Alpelisib + AZD6482 + Encorafenib AZD6482 Alpelisib Encorafenib 1 0
AZD6482 AZD6482 7 0
AZD6482 + Binimetinib AZD6482 Binimetinib 2 0
AZD6482 + Binimetinib + Encorafenib AZD6482 Binimetinib Encorafenib 0 0
AZD6482 + Binimetinib + Encorafenib + NVP-AEW541 AZD6482 Binimetinib Encorafenib NVP-AEW541 1 0
AZD6482 + Binimetinib + NVP-AEW541 AZD6482 Binimetinib NVP-AEW541 1 0
AZD6482 + Encorafenib AZD6482 Encorafenib 2 0
AZD6482 + Encorafenib + NVP-AEW541 AZD6482 Encorafenib NVP-AEW541 1 0
AZD6482 + Niraparib AZD6482 Niraparib 1 0
AZD6482 + NVP-AEW541 AZD6482 NVP-AEW541 2 0
AZD6482 + Olaparib AZD6482 Olaparib 1 0
AZD6482 + Rucaparib AZD6482 Rucaparib 1 0
AZD6482 + Talazoparib AZD6482 Talazoparib 1 0
AZD6482 + Taselisib AZD6482 Taselisib 0 0
AZD6482 + Veliparib AZD6482 Veliparib 1 0


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