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Drug Name | INCAGN01876 |
Trade Name | |
Synonyms | INCAGN1876|INCAGN-1876|INCAGN 1876 |
Drug Descriptions |
INCAGN01876 is an activating monoclonal antibody that binds to the glucocorticoid-induced tumor necrosis factor receptor, TNFRSF18 (GITR, CD357), which leads to activation of GITR and potentially results in activation of anti-tumor immunity (NCI Drug Dictionary). |
DrugClasses | GITR Antibody 7 |
CAS Registry Number | 2207590-51-8 |
NCIT ID | C126643 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
DPV-001 + INCAGN01876 + Retifanlimab | DPV-001 INCAGN01876 Retifanlimab | 0 | 1 |
Epacadostat + INCAGN01876 + Pembrolizumab | Epacadostat INCAGN01876 Pembrolizumab | 0 | 1 |
INCAGN01876 | INCAGN01876 | 0 | 1 |
INCAGN01876 + Ipilimumab | INCAGN01876 Ipilimumab | 0 | 1 |
INCAGN01876 + Ipilimumab + Nivolumab | INCAGN01876 Ipilimumab Nivolumab | 0 | 1 |
INCAGN01876 + Nivolumab | INCAGN01876 Nivolumab | 0 | 1 |
INCAGN01876 + Retifanlimab | INCAGN01876 Retifanlimab | 0 | 2 |