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Drug Name Idecabtagene Vicleucel
Trade Name Abecma
Synonyms Ide-cel|bb2121|BMS-986395
Drug Descriptions

Abecma (idecabtagene vicleucel) is a chimeric antigen receptor T cell specific to B cell maturation antigen (BCMA), which could potentially result in decreased volume of BCMA expressing tumor cells (PMID: 32707894, PMID: 33626253). Abecma (idecabtagene vicleucel) is FDA approved for use in adult patients with relapsed or refractory multiple myeloma after four or more prior lines of therapy (FDA.gov).

DrugClasses
CAS Registry Number NA
NCIT ID C117729

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bortezomib + Dexamethasone + Idecabtagene Vicleucel + Pomalidomide Bortezomib Dexamethasone Idecabtagene Vicleucel Pomalidomide 0 1
Cyclophosphamide + Fludarabine + Idecabtagene Vicleucel Cyclophosphamide Fludarabine Idecabtagene Vicleucel 0 1
Cyclophosphamide + Fludarabine + Idecabtagene Vicleucel + Lenalidomide Cyclophosphamide Fludarabine Idecabtagene Vicleucel Lenalidomide 0 0
Iberdomide + Idecabtagene Vicleucel Iberdomide Idecabtagene Vicleucel 0 1
Idecabtagene Vicleucel Idecabtagene Vicleucel 0 4
Idecabtagene Vicleucel + Lenalidomide Idecabtagene Vicleucel Lenalidomide 0 2
Idecabtagene Vicleucel + LY3039478 Idecabtagene Vicleucel LY3039478 0 1


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