Iberdomide
Drug Detail
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| Drug Name | Iberdomide |
| Trade Name | Zenbexus |
| Synonyms | CC220|CC-220|CC 220 |
| Drug Descriptions |
Zenbexus (iberdomide) binds to the ubiquitin E3 ligase complex member Cereblon (CRBN), which may lead to increased ubiquitination and degradation of transcription factors, resulting in decreased B-cell proliferation (PMID: 29945920, PMID: 28848067, PMID: 31719682). Zenbexus (iberdomide) is FDA-approved for use in combination with Darzalex Faspro (Daratumumab and hyaluronidase-fihj) and dexamethasone for adults with multiple myeloma who have received at least one prior line of therapy (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 1323403-33-3 |
| NCIT ID | C129048 |
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