Selpercatinib
Drug Detail
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| Drug Name | Selpercatinib |
| Trade Name | Retevmo |
| Synonyms | LOXO-292|LOXO292|LOXO 292|Retsevmo |
| Drug Descriptions |
Retevmo (selpercatinib) is an inhibitor of RET that specifically targets RET mutations and fusions, and may block the growth of cells with increased Ret activity (PMID: 29860229). Retevmo (selpercatinib) is FDA approved for use in patients with locally advanced or metastatic non-small cell lung cancer harboring RET fusions, and in adult and pediatric patients of 2 years and older with RET-mutant medullary thyroid cancer or RET fusion-positive thyroid cancer refractory to radioactive iodine, and in adult and pediatric patients of 2 years and older with advanced or metastatic solid tumor harboring RET fusions (FDA.org). |
| DrugClasses | RET Inhibitor 53 |
| CAS Registry Number | 2222755-14-6 |
| NCIT ID | C134987 |
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