Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | KRT-232 |
| Trade Name | |
| Synonyms | KRT 232|KRT232|AMG232|AMG 232|AMG-232|Navtemadlin |
| Drug Descriptions |
KRT-232 (AMG 232) is a potent inhibitor of the MDM2-p53 interaction, and inhibits proliferation of tumor cells in a p53 dependent manner (PMID: 24456472, PMID: 32234759). |
| DrugClasses | MDM2 Inhibitor 23 |
| CAS Registry Number | 1352066-68-2 |
| NCIT ID | C156415 |