Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Erdafitinib
Trade Name Balversa
Synonyms JNJ-42756493
Drug Descriptions

Balversa (erdafitinib) selectively inhibits FGFR1-4, resulting in decreased downstream signaling, and potentially leading to reduced growth of tumors with activated FGFR signaling (PMID: 28341788, PMID: 28965185). Balversa (erdafitinib) is FDA approved for use in patients with locally advanced or metastatic urothelial carcinoma with susceptible FGFR3 genetic alterations (FDA.gov).

DrugClasses FGFR Inhibitor (Pan) 26
CAS Registry Number 1346242-81-6
NCIT ID C103273

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Erdafitinib Abiraterone Erdafitinib 0 1
Atezolizumab + Erdafitinib Atezolizumab Erdafitinib 0 1
Cetrelimab + Erdafitinib Cetrelimab Erdafitinib 2 2
Cetuximab + Erdafitinib + Sotorasib Cetuximab Erdafitinib Sotorasib 0 0
D3S-001 + Erdafitinib D3S-001 Erdafitinib 0 0
Dexamethasone + Erdafitinib Dexamethasone Erdafitinib 0 1
Dexamethasone + Erdafitinib + Ixazomib + Pomalidomide Dexamethasone Erdafitinib Ixazomib Pomalidomide 0 1
Enfortumab vedotin-ejfv + Erdafitinib Enfortumab vedotin-ejfv Erdafitinib 0 1
Enzalutamide + Erdafitinib Enzalutamide Erdafitinib 0 1
Erdafitinib Erdafitinib 177 16
Erdafitinib + Erlotinib + Sotorasib Erdafitinib Erlotinib Sotorasib 0 0
Erdafitinib + Fulvestrant + Palbociclib Erdafitinib Fulvestrant Palbociclib 0 1
Erdafitinib + Gefitinib Erdafitinib Gefitinib 1 0
Erdafitinib + Osimertinib Erdafitinib Osimertinib 0 0
Erdafitinib + Osimertinib + Trametinib Erdafitinib Osimertinib Trametinib 0 0
Erdafitinib + Pictilisib Erdafitinib Pictilisib 1 0
Erdafitinib + Quisinostat Erdafitinib Quisinostat 1 0
Erdafitinib + Sapanisertib Erdafitinib Sapanisertib 0 0


Additional content available in CKB BOOST