Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name H3B-5942
Trade Name
Synonyms CS-0047696
Drug Descriptions

H3B-5942 is a selective estrogen receptor covalent antagonist, which antagonizes wild-type and mutant forms of estrogen receptor alpha, potentially resulting in decreased tumor cell proliferation and reduced tumor growth (PMID: 29991605).

DrugClasses Hormone - Anti-estrogens 29
CAS Registry Number 2052128-15-9
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + H3B-5942 Abemaciclib H3B-5942 0 0
AZD8055 + H3B-5942 AZD8055 H3B-5942 0 0
Everolimus + H3B-5942 Everolimus H3B-5942 0 0
H3B-5942 H3B-5942 0 0
H3B-5942 + Palbociclib H3B-5942 Palbociclib 0 0
H3B-5942 + PF-04691502 H3B-5942 PF-04691502 0 0
H3B-5942 + PKI-402 H3B-5942 PKI-402 0 0
H3B-5942 + Ribociclib H3B-5942 Ribociclib 0 0
H3B-5942 + Sirolimus H3B-5942 Sirolimus 0 0
H3B-5942 + Temsirolimus H3B-5942 Temsirolimus 0 0


Additional content available in CKB BOOST