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Drug Name | GSK690693 |
Trade Name | |
Synonyms | GSK-690693 |
Drug Descriptions |
GSK690693 is a ATP-competitive pan-AKT inhibitor, which inhibits AKT signaling, resulting in decreased proliferation and increased apoptosis of tumor cells (PMID: 18381444, PMID: 31377021). |
DrugClasses | AKT Inhibitor (Pan) - ATP competitive 7 |
CAS Registry Number | 937174-76-0 |
NCIT ID | C71711 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD0156 + GSK690693 | AZD0156 GSK690693 | 1 | 0 |
Cisplatin + GSK690693 | Cisplatin GSK690693 | 0 | 0 |
Fluorouracil + GSK690693 | Fluorouracil GSK690693 | 0 | 0 |
GSK2334470 + GSK690693 | GSK2334470 GSK690693 | 1 | 0 |
GSK690693 | GSK690693 | 7 | 0 |
GSK690693 + Imatinib | GSK690693 Imatinib | 0 | 0 |
GSK690693 + KU-57788 | GSK690693 KU-57788 | 1 | 0 |
GSK690693 + LAM-003 | GSK690693 LAM-003 | 0 | 0 |
GSK690693 + Lapatinib | GSK690693 Lapatinib | 0 | 0 |
GSK690693 + Nilotinib | GSK690693 Nilotinib | 0 | 0 |
GSK690693 + Olverembatinib | GSK690693 Olverembatinib | 0 | 0 |
GSK690693 + OSU-T315 | GSK690693 OSU-T315 | 1 | 0 |
GSK690693 + Sirolimus | GSK690693 Sirolimus | 1 | 0 |
GSK690693 + Torin 1 | GSK690693 Torin 1 | 1 | 0 |
GSK690693 + Venetoclax | GSK690693 Venetoclax | 1 | 0 |