Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name GSK690693
Trade Name
Synonyms GSK-690693
Drug Descriptions

GSK690693 is a ATP-competitive pan-AKT inhibitor, which inhibits AKT signaling, resulting in decreased proliferation and increased apoptosis of tumor cells (PMID: 18381444, PMID: 31377021).

DrugClasses AKT Inhibitor (Pan) - ATP competitive 7
CAS Registry Number 937174-76-0
NCIT ID C71711

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
AZD0156 + GSK690693 AZD0156 GSK690693 1 0
Cisplatin + GSK690693 Cisplatin GSK690693 0 0
Fluorouracil + GSK690693 Fluorouracil GSK690693 0 0
GSK2334470 + GSK690693 GSK2334470 GSK690693 1 0
GSK690693 GSK690693 7 0
GSK690693 + Imatinib GSK690693 Imatinib 0 0
GSK690693 + KU-57788 GSK690693 KU-57788 1 0
GSK690693 + LAM-003 GSK690693 LAM-003 0 0
GSK690693 + Lapatinib GSK690693 Lapatinib 0 0
GSK690693 + Nilotinib GSK690693 Nilotinib 0 0
GSK690693 + Olverembatinib GSK690693 Olverembatinib 0 0
GSK690693 + OSU-T315 GSK690693 OSU-T315 1 0
GSK690693 + Sirolimus GSK690693 Sirolimus 1 0
GSK690693 + Torin 1 GSK690693 Torin 1 1 0
GSK690693 + Venetoclax GSK690693 Venetoclax 1 0


Additional content available in CKB BOOST