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Drug Name | Inotuzumab ozogamicin |
Trade Name | Besponsa |
Synonyms | CMC-544|InO |
Drug Descriptions |
Besponsa (inotuzumab ozogamicin) consists of calecheamicin covalently linked to anti-CD22 antibody, which delivers calecheamicin into CD22-positive cells, potentially leading to DNA damage and apoptosis (PMID: 24389139). Besponsa (inotuzumab ozogamicin) is FDA-approved for use in adult and pediatric patients 1 year and older with relapsed or refractory CD22-positive B-cell precursor acute lymphoblastic leukemia (FDA.gov). |
DrugClasses | CD22 Immune Cell Therapy 15 |
CAS Registry Number | 635715-01-4 |
NCIT ID | C71542 |