Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| ID | DOID:3905 |
| Name | lung carcinoma |
| Definition | A lung cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells and is located_in the lungs and has_symptom cough and has_symptom chest discomfort or pain and has_symptom weight loss and has_symptom hemoptysis. |
| Source | DiseaseOntology.org |
| Alt Ids | |
| Path | disease disease of cellular proliferation cancer organ system cancer respiratory system cancer lung cancer lung carcinoma |
| Molecular Profile | Therapy | Indication/Tumor Type | Response Type | Profile Response Detail |
|---|---|---|---|---|
| BRAF V600E | Dasatinib | lung carcinoma | resistant | detail... |
| RB1 wild-type TP53 wild-type | R547 | lung carcinoma | sensitive | detail... |
| TP53 wild-type | Ceralasertib + Radiotherapy | lung carcinoma | sensitive | detail... |
| FGFR1 amp | Lucitanib | lung carcinoma | sensitive | detail... |
| NRAS Q61K | LY3214996 | lung carcinoma | sensitive | detail... |
| NRAS Q61K | Abemaciclib + LY3214996 | lung carcinoma | sensitive | detail... |
| PIK3CA K111R PIK3CA H1047R | STX-478 | lung carcinoma | sensitive | detail... |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02834013 | Phase II | Ipilimumab + Nivolumab | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | Active, not recruiting | USA | 1 |
| NCT02960594 | Phase I | INO-1400 + Rocakinogene sifuplasmid INO-1400 | hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse | Completed | USA | 0 |
| NCT05143970 | Phase I | IPH5301 IPH5301 + Paclitaxel + Trastuzumab | A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumors (CHANCES) | Recruiting | FRA | 0 |