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ID DOID:80202
Name adenoid cystic carcinoma
Definition An adenocarcinoma that is characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells.
Source DiseaseOntology.org
Alt Ids
Path disease disease of cellular proliferation cancer organ system cancer gastrointestinal system cancer pharynx cancer oropharynx cancer tonsil cancer adenoid cystic carcinoma

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Molecular Profile Therapy Indication/Tumor Type Response Type Profile Response Detail
FGFR2 S252W Erdafitinib adenoid cystic carcinoma predicted - sensitive detail...
Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT00770263 Phase I Erlotinib + Temsirolimus Erlotinib and Temsirolimus for Solid Tumors Completed USA 0
NCT02098538 Phase II Regorafenib Regorafenib in Patients With Progressive, Recurrent/Metastatic Adenoid Cystic Carcinoma Completed USA 0
NCT02780310 Phase II Lenvatinib Testing Lenvatinib in Patients With Adenoid Cystic Carcinoma Active, not recruiting USA 0
NCT02783300 Phase I GSK3326595 Dose Escalation Study of GSK3326595 in Participants With Solid Tumors and Non-Hodgkin's Lymphoma (NHL) Completed USA | NLD | FRA | CAN 0
NCT03087019 Phase II Pembrolizumab Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma Completed USA 0
NCT03172624 Phase II Ipilimumab + Nivolumab Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer Completed USA 0
NCT03287427 Phase I TetMYB + Tislelizumab MYPHISMO: MYB and PD-1 Immunotherapies Against Multiple Oncologies Trial (MYPHISMO) Completed AUS 0
NCT03422679 Phase Ib/II CB-103 Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies Terminated USA | FRA | ESP | DEU | CHE 1
NCT03556228 Phase I VMD-928 Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma Recruiting USA 1
NCT03691207 Phase II BMS-906024 A Study Of AL101 In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations (ACCURACY) Completed USA | NLD | ISR | GBR | FRA | CAN 0
NCT03990571 Phase II Avelumab + Axitinib Axitinib and Avelumab in Treating Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma Completed USA 0
NCT04209660 Phase II Lenvatinib + Pembrolizumab Lenvatinib and Pembrolizumab in People With Advanced Adenoid Cystic Carcinoma and Other Salivary Gland Cancers Active, not recruiting USA 0
NCT04718675 Phase Ib/II KB-0742 A Study of KB-0742 in Participants With Relapsed or Refractory Solid Tumors Including Platinum Resistant High Grade Serous Ovarian Cancer (HGSOC) Terminated USA | GBR | ESP 0
NCT04973683 Phase I BMS-906024 AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer Active, not recruiting USA 0
NCT05074940 Phase II Amivantamab-vmjw Amivantamab in Adenoid Cystic Carcinoma Active, not recruiting USA 0
NCT05774899 Phase Ib/II Abemaciclib + CB-103 CB-103 + Lenvatinib CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC Active, not recruiting USA 0
NCT05884320 Phase II Sacituzumab govitecan-hziy Phase II Trial of Sacituzumab Govitecan in Recurrent and/or Metastatic Salivary Gland Cancers Recruiting USA 0
NCT05930951 Phase I MEN1309 Balstilimab + MEN1309 Study of OBT076 Associated or Not in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma of the Head and Neck (AdCC_2023-01) Completed FRA 0
NCT06118086 Phase I REM-422 Study of REM-422 in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma Recruiting USA 0
NCT06322576 Phase II PNT2002 177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma Not yet recruiting USA 0
NCT06462183 Phase I RGT-61159 Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC) Recruiting USA | CAN 0
NCT06805617 Phase II Ivonescimab A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers (I-MAC) Recruiting USA 0
NCT06805825 Phase I NN3201 A Study of the C-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced And/or Metastatic Solid Tumors Known to Express C-Kit Recruiting USA 0
NCT06891560 Phase II Enfortumab vedotin-ejfv A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma Recruiting USA 0