Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name BAY-293
Trade Name
Synonyms BAY293|BAY 293
Drug Descriptions

BAY-293 inhibits the interaction between Sos1 and Kras, leading to reduced Ras activation and downstream Erk phosphorylation, and potentially leading to decreased tumor cell proliferation (PMID: 30683722).

DrugClasses SOS1 Inhibitor 14
CAS Registry Number 2244904-70-7
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Alvocidib + BAY-293 Alvocidib BAY-293 0 0
ARS-853 + BAY-293 ARS-853 BAY-293 0 0
BAY-293 BAY-293 0 0
BAY-293 + Cisplatin BAY-293 Cisplatin 0 0
BAY-293 + Gefitinib BAY-293 Gefitinib 0 0
BAY-293 + Osimertinib BAY-293 Osimertinib 0 0
BAY-293 + Osimertinib + RMC-4550 BAY-293 Osimertinib RMC-4550 0 0
BAY-293 + Palbociclib BAY-293 Palbociclib 0 0
BAY-293 + PD98059 BAY-293 PD98059 0 0
BAY-293 + Pemetrexed Disodium BAY-293 Pemetrexed Disodium 0 0
BAY-293 + RMC-4550 BAY-293 RMC-4550 0 0
BAY-293 + Sirolimus BAY-293 Sirolimus 0 0
BAY-293 + SN-38 BAY-293 SN-38 0 0
BAY-293 + Trametinib BAY-293 Trametinib 0 0


Additional content available in CKB BOOST