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Drug Name Rivoceranib
Trade Name
Synonyms YN968D1|Apatinib
Drug Descriptions

Rivoceranib (apatinib) is an inhibitor of receptor tyrosine kinases, including KDR (VEGFR2), RET, c-KIT, Src, and PDGFRa, which may result in reduced cell proliferation and inhibition of tumor growth (PMID: 21443688, PMID: 32669874).

DrugClasses KIT Inhibitor 57 RET Inhibitor 53 SRC Inhibitor 31 VEGFR2 Inhibitor 37
CAS Registry Number 1218779-75-9
NCIT ID C74012

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Afatinib + Rivoceranib Afatinib Rivoceranib 0 0
Camrelizumab + Rivoceranib Camrelizumab Rivoceranib 0 0
Camrelizumab + Rivoceranib + SHR9146 Camrelizumab Rivoceranib SHR9146 0 0
Capecitabine + Rivoceranib Capecitabine Rivoceranib 0 0
Everolimus + Rivoceranib Everolimus Rivoceranib 0 0
Exemestane + Rivoceranib Exemestane Rivoceranib 0 0
Gefitinib + Rivoceranib Gefitinib Rivoceranib 0 0
Icotinib + Rivoceranib Icotinib Rivoceranib 0 0
Nivolumab + Rivoceranib Nivolumab Rivoceranib 0 1
Osimertinib + Rivoceranib Osimertinib Rivoceranib 0 0
Pembrolizumab + Rivoceranib Pembrolizumab Rivoceranib 0 1
Pyrotinib + Rivoceranib Pyrotinib Rivoceranib 0 0
rhEndostatin + Rivoceranib Rivoceranib rhEndostatin 0 0
Rivoceranib Rivoceranib 0 5
Rivoceranib + Tegafur-gimeracil-oteracil Potassium Rivoceranib Tegafur-gimeracil-oteracil Potassium 0 0
Rivoceranib + Trifluridine-tipiracil hydrochloride Rivoceranib Trifluridine-tipiracil hydrochloride 0 1


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