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Drug Name Tiragolumab
Trade Name
Synonyms RO7092284|RG6058|MTIG7192A
Drug Descriptions

Tiragolumab (MTIG7192A) is an anti-human TIGIT (T cell immunoreceptor with Ig ITIM domain) antibody that potentially has anti-tumor activities through modulating the immune response to tumors (PMID: 29991503, PMID: 32576590).

DrugClasses Immune Checkpoint Inhibitor 149 TIGIT Antibody 19
CAS Registry Number 1918185-84-8
NCIT ID C131291

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Bevacizumab + Tiragolumab Atezolizumab Bevacizumab Tiragolumab 0 4
Atezolizumab + Carboplatin + Etoposide + Tiragolumab Atezolizumab Carboplatin Etoposide Tiragolumab 0 1
Atezolizumab + Carboplatin + Gemcitabine + Tiragolumab Atezolizumab Carboplatin Gemcitabine Tiragolumab 0 1
Atezolizumab + Carboplatin + Nab-paclitaxel + Tiragolumab Atezolizumab Carboplatin Nab-paclitaxel Tiragolumab 0 1
Atezolizumab + Carboplatin + Paclitaxel + Tiragolumab Atezolizumab Carboplatin Paclitaxel Tiragolumab 0 2
Atezolizumab + Carboplatin + Pemetrexed Disodium + Tiragolumab Atezolizumab Carboplatin Pemetrexed Disodium Tiragolumab 0 3
Atezolizumab + Carboplatin + Tiragolumab Atezolizumab Carboplatin Tiragolumab 0 1
Atezolizumab + Cisplatin + Fluorouracil + Tiragolumab Atezolizumab Cisplatin Fluorouracil Tiragolumab 0 1
Atezolizumab + Cisplatin + Gemcitabine + Tiragolumab Atezolizumab Cisplatin Gemcitabine Tiragolumab 0 1
Atezolizumab + Cisplatin + Pemetrexed Disodium + Tiragolumab Atezolizumab Cisplatin Pemetrexed Disodium Tiragolumab 0 2
Atezolizumab + Cisplatin + Tiragolumab Atezolizumab Cisplatin Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Filgrastim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Filgrastim Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Pegfilgrastim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Pegfilgrastim Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Sargramostim + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Sargramostim Tiragolumab 0 1
Atezolizumab + Cyclophosphamide + Doxorubicin + Tiragolumab Atezolizumab Cyclophosphamide Doxorubicin Tiragolumab 0 1
Atezolizumab + Ipilimumab + Tiragolumab Atezolizumab Ipilimumab Tiragolumab 0 1
Atezolizumab + Mosunetuzumab-axgb + Tiragolumab + Tocilizumab Atezolizumab Mosunetuzumab-axgb Tiragolumab Tocilizumab 0 1
Atezolizumab + Nab-paclitaxel + Tiragolumab Atezolizumab Nab-paclitaxel Tiragolumab 0 2
Atezolizumab + Pemetrexed Disodium + Tiragolumab Atezolizumab Pemetrexed Disodium Tiragolumab 0 1
Atezolizumab + Tiragolumab Atezolizumab Tiragolumab 0 28
Axitinib + RO7247669 + Tiragolumab Axitinib RO7247669 Tiragolumab 0 1
Daratumumab + Tiragolumab Daratumumab Tiragolumab 0 1
Ipilimumab + Tiragolumab Ipilimumab Tiragolumab 0 1
Mosunetuzumab-axgb + Tiragolumab + Tocilizumab Mosunetuzumab-axgb Tiragolumab Tocilizumab 0 1
Rituximab + Tiragolumab Rituximab Tiragolumab 0 1
RO7247669 + Tiragolumab RO7247669 Tiragolumab 0 2
Tiragolumab Tiragolumab 0 3


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