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Drug Name | Ivonescimab |
Trade Name | |
Synonyms | AK112|AK 112|AK-112|SMT112|SMT 112|SMT-112 |
Drug Descriptions |
Ivonescimab is a bispecific antibody that binds PD-1 and VEGFA, potentially resulting in antitumor activity (PMID: 37593227). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 VEGFA Antibody 4 |
CAS Registry Number | NA |
NCIT ID | C170909 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + Ivonescimab + Paclitaxel | Carboplatin Ivonescimab Paclitaxel | 0 | 1 |
Carboplatin + Ivonescimab + Pemetrexed Disodium | Carboplatin Ivonescimab Pemetrexed Disodium | 0 | 1 |
Docetaxel + Ivonescimab | Docetaxel Ivonescimab | 0 | 0 |
Ivonescimab | Ivonescimab | 0 | 5 |
Ivonescimab + Pemetrexed Disodium | Ivonescimab Pemetrexed Disodium | 0 | 1 |