Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name NKTR-214
Trade Name
Synonyms Bempegaldesleukin|Bempeg
Drug Descriptions

Bempegaldesleukin (NKTR-214) comprises IL2 bound to polyethylene glycol, which stimulates anti-tumor immune response, potentially resulting in decreased tumor growth (PMID: 26832745, PMID: 32723187).

DrugClasses
CAS Registry Number 1939126-74-5
NCIT ID C131019

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Avelumab + Enzalutamide + NKTR-214 Avelumab Enzalutamide NKTR-214 0 1
Avelumab + NKTR-214 Avelumab NKTR-214 0 1
Avelumab + NKTR-214 + Talazoparib Avelumab NKTR-214 Talazoparib 0 1
Axitinib + Nivolumab + NKTR-214 Axitinib NKTR-214 Nivolumab 0 1
Carboplatin + Nab-paclitaxel + NKTR-214 + Pembrolizumab Carboplatin NKTR-214 Nab-paclitaxel Pembrolizumab 0 1
Carboplatin + NKTR-214 + Paclitaxel + Pembrolizumab Carboplatin NKTR-214 Paclitaxel Pembrolizumab 0 1
Carboplatin + NKTR-214 + Pembrolizumab + Pemetrexed Disodium Carboplatin NKTR-214 Pembrolizumab Pemetrexed Disodium 0 1
Cisplatin + NKTR-214 + Pembrolizumab Cisplatin NKTR-214 Pembrolizumab 0 1
Mivavotinib + NKTR-214 Mivavotinib NKTR-214 0 1
Nivolumab + NKTR-214 NKTR-214 Nivolumab 0 10
Nivolumab + NKTR-214 + NKTR-262 NKTR-214 NKTR-262 Nivolumab 0 1
Nivolumab + NKTR-214 + XL092 NKTR-214 Nivolumab XL092 0 1
NKTR-214 NKTR-214 0 1
NKTR-214 + NKTR-262 NKTR-214 NKTR-262 0 1
NKTR-214 + Pembrolizumab NKTR-214 Pembrolizumab 0 3
NKTR-214 + unspecified PD-1 antibody NKTR-214 unspecified PD-1 antibody 0 0
NKTR-214 + VB10.NEO NKTR-214 VB10.NEO 0 0


Additional content available in CKB BOOST