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Drug Name | CPI-613 |
Trade Name | |
Synonyms | CPI613|CPI 613|Devimistat |
Drug Descriptions |
Devimistat (CPI-613) is an inhibitor of pyruvate dehydrogenase (PDH) and alpha-ketogluterate (KGDH), resulting in blockade of mitochondrial respiration which may lead to apoptosis and death of cancer cells (PMID: 29437791, PMID: 28495639, PMID: 32789692, PMID: 31512500). |
DrugClasses | |
CAS Registry Number | 95809-78-2 |
NCIT ID | C80039 |