BNT327
Drug Detail

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Drug Name BNT327
Trade Name
Synonyms PM8002|Pumitamig|BNT-327|BNT 327|BM-8002
Drug Descriptions

BNT327 (PM8002) is a bispecific antibody that targets VEGFA and PD-L1 (CD274), which potentially induces antitumor activity (J Clin Oncol 42, no. 16_suppl (May 29, 2024) 5524).

DrugClasses PD-L1/PD-1 antibody 132 VEGFA Antibody 5
CAS Registry Number NA
NCIT ID C200259

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Therapy Name Drugs Efficacy Evidence Clinical Trials
BNT314 + BNT327 BNT314 BNT327 0 1
BNT3212 + BNT327 BNT3212 BNT327 0 1
BNT327 BNT327 0 6
BNT327 + Capecitabine + Oxaliplatin BNT327 Capecitabine Oxaliplatin 0 2
BNT327 + Carboplatin + Etoposide BNT327 Carboplatin Etoposide 0 1
BNT327 + Carboplatin + Gemcitabine BNT327 Carboplatin Gemcitabine 0 1
BNT327 + Carboplatin + Paclitaxel BNT327 Carboplatin Paclitaxel 0 1
BNT327 + Carboplatin + Pemetrexed Disodium BNT327 Carboplatin Pemetrexed Disodium 0 1
BNT327 + DB-1303 BNT327 DB-1303 0 1
BNT327 + DB-1305 BNT327 DB-1305 0 1
BNT327 + DB-1311 BNT327 DB-1311 0 2
BNT327 + Docetaxel BNT327 Docetaxel 0 1
BNT327 + Eribulin BNT327 Eribulin 0 1
BNT327 + Fluorouracil + Irinotecan + Leucovorin BNT327 Fluorouracil Irinotecan Leucovorin 0 1
BNT327 + Fluorouracil + Leucovorin + Oxaliplatin BNT327 Fluorouracil Leucovorin Oxaliplatin 0 2
BNT327 + Nab-paclitaxel BNT327 Nab-paclitaxel 0 1
BNT327 + Paclitaxel BNT327 Paclitaxel 0 1
BNT327 + YL202 BNT327 YL202 0 2


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