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| Drug Name | Gemtuzumab ozogamicin |
| Trade Name | Mylotarg |
| Synonyms | gemtuzumab|CDP-771|CMA-676|WAY-CMA-676 |
| Drug Descriptions |
Mylotarg (gemtuzumab ozogamicin) is an antibody-drug conjugate comprising an anti-CD33 antibody linked to the cytotoxic agent calicheamicin, which results in DNA damage in CD33-expressing tumor cells (PMID: 28607471). Mylotarg (gemtuzumab ozogamicin) is FDA approved for newly-diagnosed CD33-positive acute myeloid leukemia (AML) in adult and pediatric patients 1 month and older, and in relapsed or refractory CD33-positive AML in adult and pediatric patients 2 years and older (FDA.gov). |
| DrugClasses | CD33 Antibody 13 |
| CAS Registry Number | 220578-59-6 |
| NCIT ID | C1806 |
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