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Drug Name CCS1477
Trade Name
Synonyms CCS-1477|CCS 1477
Drug Descriptions

CCS1477 binds to and inhibits p300 (EP300) and CBP (CREBBP), potentially resulting in decreased tumor cell proliferation and inhibition of tumor growth (J Clin Oncol 35, 2017 (suppl; abstr 11590)).

DrugClasses CBP/p300 inhibitor 13
CAS Registry Number 2222941-37-7
NCIT ID C160195

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + CCS1477 Abiraterone CCS1477 0 1
Atezolizumab + CCS1477 Atezolizumab CCS1477 0 1
CCS1477 CCS1477 0 2
CCS1477 + Darolutamide CCS1477 Darolutamide 0 1
CCS1477 + Enzalutamide CCS1477 Enzalutamide 0 1
CCS1477 + Olaparib CCS1477 Olaparib 0 1


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