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Drug Name | Bintrafusp alfa |
Trade Name | |
Synonyms | MSB0011359C|M7824 |
Drug Descriptions |
Bintrafusp alfa is a human PD-L1 (CD274) antibody fused with transforming growth factor-beta (TGF-beta, TGFBR2) receptor II extracellular domain, which blocks two immuno-inhibitory pathways simultaneously, therefore enhances anti-tumor immunity (PMID: 29298798, PMID: 32461347). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 TGFBR2 Antibody 3 |
CAS Registry Number | 1918149-01-5 |
NCIT ID | C124229 |