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Drug Name ETBX-051
Trade Name
Synonyms ETBX051|ETBX 051
Drug Descriptions

ETBX-051 is a virally based vaccine that infects cells and induces expression of the brachyury protein protein, which may activate the immune system to elicit a cytotoxic T-lymphocyte (CTL) response against brachyury expressing tumor cells (PMID: 31594913).

DrugClasses
CAS Registry Number 2171537-82-7
NCIT ID C143034

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldoxorubicin + Avelumab + Bevacizumab + Capecitabine + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + Gemcitabine + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Nogapendekin alfa inbakicept + Oxaliplatin Aldoxorubicin Avelumab Bevacizumab Capecitabine Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Gemcitabine Leucovorin Nab-paclitaxel Nogapendekin alfa inbakicept Oxaliplatin haNK cells 0 2
Aldoxorubicin + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-021 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Nogapendekin alfa inbakicept + Oxaliplatin + Regorafenib + Trastuzumab Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-021 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Nogapendekin alfa inbakicept Oxaliplatin Regorafenib Trastuzumab haNK cells 0 1
Aldoxorubicin + Avelumab + Capecitabine + Cetuximab + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Nogapendekin alfa inbakicept + Sorafenib Aldoxorubicin Avelumab Capecitabine Cetuximab Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Nogapendekin alfa inbakicept Sorafenib haNK cells 0 1
Aldoxorubicin + Avelumab + Cetuximab + ETBX-051 + ETBX-061 + GI-6301 + haNK cells + Nogapendekin alfa inbakicept Aldoxorubicin Avelumab Cetuximab ETBX-051 ETBX-061 GI-6301 Nogapendekin alfa inbakicept haNK cells 0 1
Aldoxorubicin + Avelumab + Cisplatin + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6301 + haNK cells + Nogapendekin alfa inbakicept + Paclitaxel Aldoxorubicin Avelumab Cisplatin Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6301 Nogapendekin alfa inbakicept Paclitaxel haNK cells 0 1
Aldoxorubicin + Avelumab + Cyclophosphamide + ETBX-011 + ETBX-051 + ETBX-061 + Fluorouracil + GI-4000 + GI-6207 + GI-6301 + haNK cells + Leucovorin + Nab-paclitaxel + Nogapendekin alfa inbakicept Aldoxorubicin Avelumab Cyclophosphamide ETBX-011 ETBX-051 ETBX-061 Fluorouracil GI-4000 GI-6207 GI-6301 Leucovorin Nab-paclitaxel Nogapendekin alfa inbakicept haNK cells 0 1
Bintrafusp alfa + ETBX-011 + ETBX-051 + ETBX-061 Bintrafusp alfa ETBX-011 ETBX-051 ETBX-061 0 1
Bintrafusp alfa + ETBX-011 + ETBX-051 + ETBX-061 + Nogapendekin alfa inbakicept Bintrafusp alfa ETBX-011 ETBX-051 ETBX-061 Nogapendekin alfa inbakicept 0 1
ETBX-011 + ETBX-051 + ETBX-061 ETBX-011 ETBX-051 ETBX-061 0 1
ETBX-011 + ETBX-051 + ETBX-061 + Nogapendekin alfa inbakicept + Retifanlimab ETBX-011 ETBX-051 ETBX-061 Nogapendekin alfa inbakicept Retifanlimab 0 1
ETBX-011 + ETBX-051 + ETBX-061 + Nogapendekin alfa inbakicept + Retifanlimab + SX-682 ETBX-011 ETBX-051 ETBX-061 Nogapendekin alfa inbakicept Retifanlimab SX-682 0 1
ETBX-051 ETBX-051 0 2
ETBX-051 + ETBX-061 + ETBX-071 ETBX-051 ETBX-061 ETBX-071 0 1


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