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| Drug Name | Loncastuximab tesirine-lpyl |
| Trade Name | Zynlonta |
| Synonyms | ADCT-402 |
| Drug Descriptions |
Zynlonta (loncastuximab tesirine-lpyl) is a human anti-CD19 antibody in conjugation with a pyrrolobenzodiazepine (PBD) dimer toxin, which may specifically target CD19-positive tumor cells (Blood 2017 130(Suppl 1):187, PMID: 32012214). Zynlonta (loncastuximab tesirine-lpyl) is FDA approved for use in patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy (FDA.gov). |
| DrugClasses | CD19 Antibody 21 |
| CAS Registry Number | 1879918-31-6 |
| NCIT ID | C125549 |
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