Epcoritamab-bysp
Drug Detail
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| Drug Name | Epcoritamab-bysp |
| Trade Name | Epkinly |
| Synonyms | DuoBody-CD3xCD20|GEN 3013|GEN-3013|GEN3013|epcoritamab |
| Drug Descriptions |
Epkinly (epcoritamab-bysp) is a bispecific antibody that targets CD3 and CD20, resulting in T-cell activation and redirection of T-cells to CD20-expressing tumor cells, which may lead to tumor cell cytotoxicity and inhibition of tumor growth (PMID: 31981978, PMID: 33602901). Epkinly (epcoritamab-bysp) is FDA-approved for use in patients with relapsed or refractory diffuse large B-cell lymphoma, high-grade B-cell lymphoma, and follicular lymphoma after two or more lines of systemic therapy and in combination with Revlimid (lenalidomide) and Rituxan (rituximab) in patients with relapsed/refractory follicular lymphoma (FDA.gov). |
| DrugClasses | CD20 Antibody 26 CD3 Antibody 119 |
| CAS Registry Number | 2134641-34-0 |
| NCIT ID | C163022 |
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