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| Drug Name | Umbralisib |
| Trade Name | Ukoniq |
| Synonyms | RP5264|TGR-1202 |
| Drug Descriptions |
Ukoniq (umbralisib) is a selective inhibitor of PIK3CD, which prevents Akt phosphorylation and induces cytotoxicity (J Clin Oncol 32:5s, 2014 (suppl; abstr 2513), PMID: 30709431). Ukoniq (umbralisib) is FDA approved for use in adult patients with relapsed or refractory marginal zone lymphoma with one or more prior anti-CD20-based therapy, and in adult patients with relapsed or refractory follicular lymphoma who have three or more prior lines of therapy (FDA.gov). |
| DrugClasses | PIK3CD inhibitor 27 |
| CAS Registry Number | 1532533-67-7 |
| NCIT ID | C104413 |
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