Ziftomenib
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| Drug Name | Ziftomenib |
| Trade Name | Komzifti |
| Synonyms | KO539|KO 539|KO-539 |
| Drug Descriptions |
Komzifti (ziftomenib) is a small molecule inhibitor of MEN1 (menin)-KMT2A (MLL1) complex, which may lead to decreased growth KMT2A (MLL1)-positive tumor cells, and inhibition of tumor growth (PMID: 36151141). Komzifti (ziftomenib) is FDA-approved for use in patients with relapsed/refractory acute myeloid leukemia harboring a susceptible NPM1 mutation (FDA.gov). |
| DrugClasses | MEN1-KMT2A Inhibitor 8 |
| CAS Registry Number | 2134675-36-6 |
| NCIT ID | C164227 |
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