Azenosertib
Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Azenosertib
Trade Name
Synonyms ZNc3|ZN c3|ZN-c3
Drug Descriptions

Azenosertib inhibits WEE1, which potentially increases DNA damage leading to induction of apoptosis, decreased tumor cell proliferation, and inhibition of tumor growth (PMID: 40231599, PMID: 39755818).

DrugClasses WEE1 Inhibitor 8
CAS Registry Number 2376146-48-2
NCIT ID C167064

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Adagrasib + Azenosertib Adagrasib Azenosertib 0 0
Azenosertib Azenosertib 0 6
Azenosertib + Bevacizumab Azenosertib Bevacizumab 0 1
Azenosertib + Bevacizumab + Pembrolizumab Azenosertib Bevacizumab Pembrolizumab 0 1
Azenosertib + Carboplatin Azenosertib Carboplatin 0 1
Azenosertib + Carboplatin + Pembrolizumab Azenosertib Carboplatin Pembrolizumab 0 1
Azenosertib + Cetuximab + Encorafenib Azenosertib Cetuximab Encorafenib 0 1
Azenosertib + Daraxonrasib Azenosertib Daraxonrasib 0 0
Azenosertib + Gemcitabine Azenosertib Gemcitabine 0 1
Azenosertib + Niraparib Azenosertib Niraparib 0 1
Azenosertib + Paclitaxel Azenosertib Paclitaxel 0 0
Azenosertib + Pegylated liposomal doxorubicin Azenosertib Pegylated liposomal doxorubicin 0 1
Azenosertib + Pembrolizumab Azenosertib Pembrolizumab 0 1
Azenosertib + Sotorasib Azenosertib Sotorasib 0 0
Azenosertib + Talazoparib Azenosertib Talazoparib 0 1
Azenosertib + Trastuzumab deruxtecan Azenosertib Trastuzumab deruxtecan 0 1
Azenosertib + ZN-d5 Azenosertib ZN-d5 0 1


Additional content available in Icon for CKB-BoostCKB BOOST