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Drug Name | Blinatumomab |
Trade Name | Blincyto |
Synonyms | anti-CD19/anti-CD3 recombinant bispecific|monoclonal antibody MT103|MEDI-538 |
Drug Descriptions |
Blincyto (blinatumomab) is a bispecific antibody that binds both CD19 on B-cells and the CD3 complex on T-cells, therefore facilitates T-cell mediated killing of CD19-expressing tumor cells (PMID: 26337639). Blincyto (blinatumomab) is FDA-approved for use in adult and pediatric patients one month and older with relapsed or refractory CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL), CD19-positive B-cell precursor ALL in remission, and CD19-positive, BCR-ABL1-negative B-cell precursor ALL in the consolidation phase (FDA.gov). |
DrugClasses | CD19 Antibody 21 |
CAS Registry Number | 853426-35-4 |
NCIT ID | C62528 |