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| Drug Name | Ceritinib |
| Trade Name | Zykadia |
| Synonyms | LDK378 |
| Drug Descriptions |
Zykadia (ceritinib) inhibits ALK, including ALK mutations and fusions, and has additional activity against ROS1 fusions, potentially resulting in decreased tumor cell growth (PMID: 25322323, PMID: 26372962). Zykadia (ceritinib) is FDA approved for ALK-positive (rearrangements and fusions) metastatic non-small cell lung cancer (FDA.gov). |
| DrugClasses | ALK Inhibitor 33 ROS1 Inhibitor 22 |
| CAS Registry Number | 1032900-25-6 |
| NCIT ID | C115112 |
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