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Drug Name Leuprolide
Trade Name Lupron
Synonyms Leuprorelin
Drug Descriptions

Lupron (leuprolide) is an agonist of gonadotropin releasing hormone (GnRH), which results decreased testosterone production in males and decreased estradiol production in females, potentially leading to decreased growth of androgen-positive tumors (NCI Drug Dictionary).

DrugClasses
CAS Registry Number 53714-56-0
NCIT ID C62042

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abemaciclib + Darolutamide + Degarelix + Goserelin + Leuprolide Abemaciclib Darolutamide Degarelix Goserelin Leuprolide 0 1
Abemaciclib + Letrozole + Leuprolide Abemaciclib Letrozole Leuprolide 0 1
Abiraterone + Apalutamide + Leuprolide Abiraterone Apalutamide Leuprolide 0 3
Abiraterone + Apalutamide + Leuprolide + Prednisone Abiraterone Apalutamide Leuprolide Prednisone 0 2
Abiraterone + Atezolizumab + Leuprolide + Prednisone Abiraterone Atezolizumab Leuprolide Prednisone 0 1
Abiraterone + Bicalutamide + Leuprolide + Prednisone + Talazoparib Abiraterone Bicalutamide Leuprolide Prednisone Talazoparib 0 1
Abiraterone + Leuprolide Abiraterone Leuprolide 0 1
Abiraterone + Leuprolide + Niraparib + Prednisone Abiraterone Leuprolide Niraparib Prednisone 0 1
Abiraterone + Leuprolide + Prednisone Abiraterone Leuprolide Prednisone 0 2
Anastrozole + Exemestane + Letrozole + Leuprolide + Tamoxifen Anastrozole Exemestane Letrozole Leuprolide Tamoxifen 0 0
Anastrozole + Leuprolide + Ribociclib Anastrozole Leuprolide Ribociclib 0 1
Anastrozole + Leuprolide + Tamoxifen Anastrozole Leuprolide Tamoxifen 0 1
Apalutamide + Leuprolide Apalutamide Leuprolide 0 5
Avelumab + Leuprolide Avelumab Leuprolide 0 1
Avelumab + Leuprolide + Palbociclib Avelumab Leuprolide Palbociclib 0 1
Azacitidine + Leuprolide + Tretinoin Azacitidine Leuprolide Tretinoin 0 1
Bicalutamide + Docetaxel + Flutamide + Goserelin + Leuprolide + Nilutamide Bicalutamide Docetaxel Flutamide Goserelin Leuprolide Nilutamide 0 1
Bicalutamide + Docetaxel + Leuprolide Bicalutamide Docetaxel Leuprolide 0 2
Bicalutamide + Flutamide + Goserelin + Leuprolide + Nilutamide Bicalutamide Flutamide Goserelin Leuprolide Nilutamide 0 1
Bicalutamide + HSV-Tk + Leuprolide + Valacyclovir Bicalutamide HSV-Tk Leuprolide Valacyclovir 0 1
Bicalutamide + Leuprolide Bicalutamide Leuprolide 0 3
Bicalutamide + Leuprolide + Pembrolizumab Bicalutamide Leuprolide Pembrolizumab 0 1
Cemiplimab + Degarelix + Docetaxel + Leuprolide Cemiplimab Degarelix Docetaxel Leuprolide 0 1
Cemiplimab + Degarelix + Leuprolide Cemiplimab Degarelix Leuprolide 0 0
Darolutamide + Degarelix + Goserelin + Leuprolide Darolutamide Degarelix Goserelin Leuprolide 0 1
Darolutamide + Exemestane + Leuprolide Darolutamide Exemestane Leuprolide 0 1
Darolutamide + Leuprolide Darolutamide Leuprolide 0 3
Degarelix + Enzalutamide + Leuprolide + Talazoparib Degarelix Enzalutamide Leuprolide Talazoparib 0 0
Docetaxel + Leuprolide Docetaxel Leuprolide 0 1
Enzalutamide + Leuprolide Enzalutamide Leuprolide 0 2
Enzalutamide + Leuprolide + Talazoparib Enzalutamide Leuprolide Talazoparib 0 1
Exemestane + Leuprolide + Ribociclib Exemestane Leuprolide Ribociclib 0 1
Exemestane + Leuprolide + Tamoxifen Exemestane Leuprolide Tamoxifen 0 1
Flutamide + Leuprolide Flutamide Leuprolide 0 1
Goserelin + Leuprolide Goserelin Leuprolide 0 1
Letrozole + Leuprolide + Ribociclib Letrozole Leuprolide Ribociclib 0 1
Letrozole + Leuprolide + Tamoxifen Letrozole Leuprolide Tamoxifen 0 1
Leuprolide Leuprolide 0 51
Leuprolide + Olaparib Leuprolide Olaparib 0 1
Leuprolide + Palbociclib Leuprolide Palbociclib 0 1
Leuprolide + Pertuzumab + Ribociclib + Trastuzumab Leuprolide Pertuzumab Ribociclib Trastuzumab 0 1
Leuprolide + Radium Ra 223 dichloride Leuprolide Radium Ra 223 dichloride 0 1
Leuprolide + Testosterone cypionate Leuprolide Testosterone cypionate 0 1


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