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| Drug Name | Capivasertib |
| Trade Name | Truqap |
| Synonyms | AZD5363|AZD 5363|AZD-5363 |
| Drug Descriptions |
Truqap (capivasertib) decreases PI3K/AKT/mTOR signaling by inhibition of AKT1, AKT2, and AKT3, potentially resulting in decreased cell proliferation (PMID: 22294718, PMID: 32532747, PMID: 32312891). Truqap (capivasertib) in combination with Faslodex (fulvestrant) is FDA-approved for use in patients with hormone receptor-positive, ERBB2 (HER2)-negative, locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN-alterations (FDA.gov). |
| DrugClasses | Akt Inhibitor (Pan) 21 |
| CAS Registry Number | 1143532-39-1 |
| NCIT ID | C102564 |
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