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Drug Name Tafasitamab-cxix
Trade Name Monjuvi
Synonyms MOR00208|XmAb5574|MOR-208|MOR208|Tafasitamab
Drug Descriptions

Monjuvi (tafasitamab-cxix) is an CD19-targeted antibody with an engineered Fc region, which may result in an increased antibody-dependent cell-mediated cytotoxicity response against CD19-expressing tumor cells (PMID: 23277329, PMID: 32511983). Monjuvi (tafasitamab-cxix) is FDA approved for use in combination with Revlimid (lenalidomide) in patients with relapsed or refractory diffuse large B cell lymphoma (FDA.gov).

DrugClasses CD19 Antibody 21
CAS Registry Number 1422527-84-1
NCIT ID C95768

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Acalabrutinib + Cyclophosphamide + Doxorubicin + Lenalidomide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Acalabrutinib Cyclophosphamide Doxorubicin Lenalidomide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Acalabrutinib + Lenalidomide + Rituximab + Tafasitamab-cxix Acalabrutinib Lenalidomide Rituximab Tafasitamab-cxix 0 1
Acalabrutinib + Obinutuzumab + Tafasitamab-cxix Acalabrutinib Obinutuzumab Tafasitamab-cxix 0 1
Acalabrutinib + Tafasitamab-cxix Acalabrutinib Tafasitamab-cxix 0 1
Bendamustine + Tafasitamab-cxix Bendamustine Tafasitamab-cxix 0 1
Carboplatin + Etoposide + Ifosfamide + Lenalidomide + Tafasitamab-cxix Carboplatin Etoposide Ifosfamide Lenalidomide Tafasitamab-cxix 0 1
Cyclophosphamide + Doxorubicin + Etoposide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Etoposide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Lenalidomide + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Lenalidomide Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 2
Cyclophosphamide + Doxorubicin + Prednisone + Retifanlimab + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Prednisone Retifanlimab Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Prednisone + Rituximab + Tafasitamab-cxix + Vincristine Sulfate Cyclophosphamide Doxorubicin Prednisone Rituximab Tafasitamab-cxix Vincristine Sulfate 0 1
Iberdomide + Lenalidomide + Tafasitamab-cxix Iberdomide Lenalidomide Tafasitamab-cxix 0 0
Iberdomide + Tafasitamab-cxix Iberdomide Tafasitamab-cxix 0 1
Ibrutinib + Tafasitamab-cxix Ibrutinib Tafasitamab-cxix 0 1
Idelalisib + Tafasitamab-cxix Idelalisib Tafasitamab-cxix 0 1
Lenalidomide + Methotrexate + Rituximab + Tafasitamab-cxix Lenalidomide Methotrexate Rituximab Tafasitamab-cxix 0 1
Lenalidomide + Mosunetuzumab-axgb + Polatuzumab vedotin-piiq + Tafasitamab-cxix Lenalidomide Mosunetuzumab-axgb Polatuzumab vedotin-piiq Tafasitamab-cxix 0 1
Lenalidomide + Rituximab + Tafasitamab-cxix Lenalidomide Rituximab Tafasitamab-cxix 0 2
Lenalidomide + Selinexor + Tafasitamab-cxix Lenalidomide Selinexor Tafasitamab-cxix 0 1
Lenalidomide + Tafasitamab-cxix Lenalidomide Tafasitamab-cxix 0 9
Lenalidomide + Tafasitamab-cxix + Tazemetostat Lenalidomide Tafasitamab-cxix Tazemetostat 0 2
Lenalidomide + Tafasitamab-cxix + Temozolomide Lenalidomide Tafasitamab-cxix Temozolomide 0 0
Lenalidomide + Tafasitamab-cxix + TTI-622 Lenalidomide TTI-622 Tafasitamab-cxix 0 1
Lenalidomide + Tafasitamab-cxix + Venetoclax Lenalidomide Tafasitamab-cxix Venetoclax 0 1
Lenalidomide + Tafasitamab-cxix + XmAb13676 Lenalidomide Tafasitamab-cxix XmAb13676 0 1
Lenalidomide + Tafasitamab-cxix + Zanubrutinib Lenalidomide Tafasitamab-cxix Zanubrutinib 0 1
Parsaclisib + Tafasitamab-cxix Parsaclisib Tafasitamab-cxix 0 1
Tafasitamab-cxix Tafasitamab-cxix 0 1
Tafasitamab-cxix + Venetoclax Tafasitamab-cxix Venetoclax 0 1
Tafasitamab-cxix + Zanubrutinib Tafasitamab-cxix Zanubrutinib 0 2


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