Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name Parsaclisib
Trade Name
Synonyms INCB050465|INCB 50465|INCB-50465|INCB50465|WHO 10589
Drug Descriptions

Parsaclisib (INCB050465) inhibits PI3K-delta, blocking activation of AKT signaling pathway and leading to apoptosis of PIK3CD expressing tumor cells (PMID: 31749910).

DrugClasses PIK3CD inhibitor 27
CAS Registry Number 1426698-88-5
NCIT ID C113434

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Bendamustine + Obinutuzumab + Parsaclisib Bendamustine Obinutuzumab Parsaclisib 0 1
Bendamustine + Parsaclisib + Rituximab Bendamustine Parsaclisib Rituximab 0 1
Cyclophosphamide + Doxorubicin + Parsaclisib + Pegfilgrastim + Polatuzumab vedotin-piiq + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Parsaclisib Pegfilgrastim Polatuzumab vedotin-piiq Prednisone Rituximab Vincristine Sulfate 0 1
Cyclophosphamide + Doxorubicin + Parsaclisib + Pegfilgrastim + Prednisone + Rituximab + Vincristine Sulfate Cyclophosphamide Doxorubicin Parsaclisib Pegfilgrastim Prednisone Rituximab Vincristine Sulfate 0 1
Ibrutinib + Parsaclisib Ibrutinib Parsaclisib 0 1
INCB053914 + Parsaclisib INCB053914 Parsaclisib 0 1
Itacitinib + Parsaclisib Itacitinib Parsaclisib 0 3
Parsaclisib Parsaclisib 0 6
Parsaclisib + Pembrolizumab Parsaclisib Pembrolizumab 0 1
Parsaclisib + Retifanlimab Parsaclisib Retifanlimab 0 1
Parsaclisib + Rituximab Parsaclisib Rituximab 0 1
Parsaclisib + Romidepsin Parsaclisib Romidepsin 0 1
Parsaclisib + Ruxolitinib Parsaclisib Ruxolitinib 0 3
Parsaclisib + Tafasitamab-cxix Parsaclisib Tafasitamab-cxix 0 1


Additional content available in CKB BOOST