Dasatinib
Drug Detail
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| Drug Name | Dasatinib |
| Trade Name | Sprycel |
| Synonyms | BMS-354825 |
| Drug Descriptions |
Sprycel (dasatinib) is an inhibitor of the SRC-family of protein kinases, BCR-ABL, and ABL, and has additional activity against other kinases including KIT, DDR1/2, PDGFRA/B, and EPHA2, which prevents cell growth (PMID: 25709401, PMID: 25284748, PMID: 18797457, PMID: 23942795). Sprycel (dasatinib) is FDA approved for both Philadelphia chromosome positive adult and pediatric chronic myelogenous leukemia and adult acute lymphoblastic leukemia (FDA.gov). |
| DrugClasses | ABL Inhibitor (pan) 9 BCR-ABL Inhibitor 32 BTK inhibitor 38 CSF1R Inhibitor 28 DDR1 Inhibitor 10 DDR2 inhibitor 7 KIT Inhibitor 57 PDGFR Inhibitor (Pan) 30 SRC Inhibitor 31 TNK2 Inhibitor 7 |
| CAS Registry Number | 863127-77-9 |
| NCIT ID | C38713 |
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